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Carboplatin
    Publish time 2024-10-17 17:28    

CAS Number: 41575-94-4

Carboplatin

Basic Information

  • Product Name: Carboplatin

  • CAS Number: 41575-94-4

  • Molecular Formula: C6H12N2O4Pt

  • Molecular Weight: 371.254 g/mol

  • Appearance: White crystalline powder

Physical Properties

  • Boiling Point: 366.4ºC at 760 mmHg

  • Melting Point: 228-230ºC

  • Flash Point: 189.6ºC

  • Solubility: Sparingly soluble in water, very slightly soluble in acetone and in ethanol (96%).

Chemical Properties

  • Stability: Stable under normal conditions, incompatible with strong oxidizing agents.

  • pH: Not specifically mentioned, but typically platinum-based compounds may have neutral or slightly acidic pH values.

Mechanism of Action

Carboplatin is a DNA synthesis inhibitor. It binds to DNA, inhibiting replication and transcription, and ultimately inducing cell death. This makes it an effective anticancer agent.

Uses

Carboplatin is primarily used in the treatment of various types of cancers, including small cell lung cancer, ovarian cancer, testicular cancer, head and neck squamous cell carcinoma, non-small cell lung cancer, bladder cancer, cervical cancer, liver cancer, and others. It can also be used in radiation enhancement therapy.