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Oxaliplatin
    Publish time 2024-10-17 10:24    

CAS Number: 61825-94-3

Oxaliplatin

asic Information

  • Product Name: Oxaliplatin.

  • CAS Number: 61825-94-3 

  • Molecular Formula: C8H14N2O4Pt (or C6H14N2C2O4Pt, representing the same formula but written differently).

  • Molecular Weight: 397.29.

Physical Properties

  • Appearance: White to grayish-white solid powder (alternatively described as white or almost white crystalline powder).

  • Density: 1.1360.

  • Solubility: Soluble in water at 2.17 mg/mL, soluble in DMF at 1.67 mg/mL, and less soluble in ethanol at less than 1 mg/mL.

Chemical Properties

  • Mechanism of Action: Oxaliplatin is a platinum-based DNA crosslinking agent that induces the formation of inter- and intra-strand crosslinks in DNA, as well as DNA-protein crosslinks, inhibiting DNA and RNA synthesis and inducing apoptotic cell death.

  • Incompatibility: It is incompatible with sodium chloride and alkaline solutions, as well as alkaline drugs (especially 5-fluorouracil). Do not dissolve or dilute this drug with saline solution