Molecular Formula: C32H37NO8 (or C26H29NO·C6H8O7, considering the citrate moiety)
Molecular Weight: 563.64 (or 563.638, depending on calculation precision)
Purity: Typically 99% or higher, such as 99.87%
Appearance: White to off-white powder
II. Physical Properties
Melting Point: 140-144°C
Boiling Point: 665.9°C at 760 mmHg (note: actual boiling point may vary depending on conditions)
Flash Point: 356.5°C
Storage Conditions: Usually recommended to be stored under seal at 2-8°C, protected from light. Some sources suggest storage at -20°C, and once dissolved in a solvent, it should be used within one month if stored at -20°C.
Mechanism of Action: Tamoxifen Citrate competitively binds to estrogen receptors, thereby blocking the action of estrogen in breast cells and activating estrogen activity in other cells (such as bone, liver, and uterine cells). It also acts as an Hsp90 activator, enhancing the ATPase activity of Hsp90 molecular chaperones.
