I. Basic Information

• Product Name: Bendamustine Hydrochloride

• CAS Number: 3543-75-7

• Molecular Formula: C16H22Cl3N3O2

• Molecular Weight: 394.724

II. Physical Properties

• Appearance: Solid, ranging in color from white to yellow

• Melting Point: 149-151°C

III. Chemical Properties

• Category: Purine analog, DNA crosslinking agent

• Mechanism of Action: It exhibits alkylating, anticancer, and antimetabolic activities, activating DNA damage responses and apoptosis. It causes DNA strand breaks and uniquely modulates both apoptotic pathways and DNA repair pathways in non-Hodgkin's lymphoma cells.