Purity: ≥98% (typically, can vary by manufacturer)
Physical Properties
Appearance: White to off-white solid
Storage Conditions: It should be stored at -25°C to -15°C for powdered form, with a shelf life of 3 years. When dissolved in a solvent, it should be stored at -85°C to -65°C, with a shelf life of 2 years. Alternatively, it can be stored at -20°C, but it is recommended to use within one month after dissolution.
Pharmaceutical Properties
Antibiotic Class: Cefotiam hydrochloride belongs to the second-generation cephalosporin antibiotics.
Spectrum of Activity: It exhibits broad-spectrum activity against both Gram-positive and Gram-negative bacteria.
Mechanism of Action: By binding to penicillin-binding proteins (PBPs), it inhibits the synthesis of bacterial cell walls, thereby exerting bactericidal activity.
Safety and Handling
Hazards: It is irritant and should not be inhaled, ingested, or come into contact with skin or eyes.
Protective Measures: Wear protective clothing, gloves, and eye protection during handling. Avoid repeated freeze-thaw cycles and store in a dry, dark place.
Intended Use: Cefotiam hydrochloride is intended for research purposes only and should not be used clinically or for any other purposes.
