Basic Information

• Chemical Name: Fusidic Acid

• CAS Number: 6990-06-3

• Molecular Formula: C31H48O6

• Molecular Weight: 516.71 g/mol

Physical Properties

• Appearance: White to off-white solid

• Melting Point: Approximately 190-192°C

• Density: Various reported values, typically around 1.16±0.1 g/cm3 or 1.2±0.1 g/cm3

• Boiling Point: Approximately 635.6±55.0°C

• Solubility: Practically insoluble in water but freely soluble in organic solvents such as chloroform, ethanol, acetone, and dioxane. Slightly soluble in ether.

Chemical Properties and Mechanism of Action

• Chemical Classification: Fusidic Acid belongs to the fusidic acid antibiotics, which have a steroidal skeleton similar to cephalosporins but are not hormones.

• Mechanism of Action: It inhibits bacterial growth by preventing the ribosome from releasing the translational elongation factor G (EF-G), thereby interfering with bacterial protein synthesis.