Solubility: Slightly soluble in water, very slightly soluble in ethanol
Melting Point: Approximately 197°C (estimated)
Chemical Properties and Antibacterial Activity
Cefadroxil Monohydrate is a cephalosporin antibiotic with broad-spectrum antibacterial activity.
It is effective against both Gram-positive and Gram-negative bacteria.
Cefadroxil Monohydrate demonstrates antibacterial activity against Staphylococcus aureus (both penicillinase-producing and non-producing strains), Staphylococcus epidermidis, Streptococcus pneumoniae, Streptococcus pyogenes, Escherichia coli, Proteus mirabilis, Salmonella species, Shigella species, Haemophilus influenzae, and Neisseria gonorrhoeae, among others.
However, it is resistant to methicillin-resistant Staphylococcus aureus, Enterococcus species, indole-positive Proteus species, Enterobacteriaceae, Serratia species, and Pseudomonas aeruginosa.
Pharmaceutical Characteristics and Uses
Cefadroxil Monohydrate is an orally administered first-generation cephalosporin with good absorption, a broad antibacterial spectrum, good efficacy, and low toxicity.
It is used to treat various infections caused by susceptible bacteria, including urinary tract infections, respiratory infections, skin and soft tissue infections, otitis media, and bone and joint infections.
