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Itopride Hydrochloride
    Publish time 2024-09-30 14:51    

CAS No.: 122892-31-3

Itopride Hydrochloride

Basic Chemical Information

  • English Name: Itopride Hydrochloride

  • Molecular Formula: C20H26N2O4·HCl

  • Molecular Weight: 394.90

  • CAS Number: 122892-31-3

Pharmacological Effects

  • Gastric Motility Enhancement: Itopride Hydrochloride enhances gastrointestinal motility by increasing the release of acetylcholine.

  • Increased Gastric Pepsin Activity: The drug inhibits the secretion of somatostatin by D cells, indirectly stimulating the release of gastrin by E cells, which in turn prompts G cells to release pepsinogen, converting it into active pepsin, thereby facilitating the digestion of protein in food.

  • Improved Digestion and Absorption: By directly acting on smooth muscles and relieving their spasms, Itopride Hydrochloride promotes gastrointestinal motility, accelerates food emptying, and thus improves digestive function.

  • Relief of Abdominal Bloating: By stimulating upper gastrointestinal motility, Itopride Hydrochloride improves postprandial symptoms in patients with functional dyspepsia, such as abdominal bloating and belching.

  • Antiemetic Effect: Itopride Hydrochloride can selectively block central dopamine receptors, reducing the frequency of nausea and vomiting.