English Name: Mosapride Citrate Molecular Formula: C27H33ClFN3O10 Molecular Weight: 614.020 CAS Number: 112885-42-4
Pharmacological Effects:
1.Stimulating Gastrointestinal Motility: Mosapride citrate acts as a 5-HT4 receptor agonist, enhancing the release of acetylcholine which promotes gastrointestinal motility. It helps alleviate symptoms like bloating and constipation by accelerating gastric emptying and improving intestinal transit.
2.Antiemetic Properties: Due to its effect on serotonin receptors, mosapride citrate can also reduce nausea and vomiting by stabilizing gastrointestinal movements and preventing excessive muscle contractions.
3.Gastroprokinetic Agent: By increasing gastrointestinal peristalsis, mosapride citrate is effective in managing conditions like gastroesophageal reflux disease (GERD) and functional dyspepsia.
4.Improving Blood Flow: It may also enhance blood flow in the gut mucosa, promoting better digestion and nutrient absorption.
5.Safety Profile: Mosapride citrate has a favorable safety profile, with fewer central nervous system side effects compared to other prokinetic agents due to its minimal ability to cross the blood-brain barrier.
