Chemical Information
- English Name: Irsogladine Maleate
- Molecular Formula: C19H24N4O4 . C4H4O4
- Molecular Weight: 460.48 g/mol
- CAS Number: 77392-84-0

Pharmacological Action
1. Mucosal Protective Effect: Irsogladine Maleate enhances the mucosal defense mechanism of the gastrointestinal tract, promoting mucosal protection and repair. It achieves this by increasing intracellular cyclic AMP (cAMP) levels, which leads to enhanced mucosal blood flow and mucus production.

1.     Inhibition of Inflammation: The drug inhibits the release of inflammatory mediators such as leukotrienes and histamine, thus playing an anti-inflammatory role in the gastrointestinal mucosa.

2.     Enhancement of Intercellular Communication: Irsogladine Maleate improves gap junction intercellular communication, which is crucial for maintaining the integrity and function of epithelial cells in the gastrointestinal tract.

3.     Antisecretory Effects: It reduces gastric acid secretion, which can be beneficial in preventing and treating conditions like gastritis and peptic ulcer disease.

4.     Cytoprotective Actions: By enhancing the defense mechanisms of the gastric mucosa, irsogladine maleate exerts cytoprotective effects, helping to prevent and heal mucosal damage.

5.     Improvement in Tissue Repair: The drug promotes the healing process in damaged mucosa by ensuring proper cell regeneration and repair mechanisms.