Mecobalamin, also known as Methylcobalamin, is an active form of Vitamin B12 that plays crucial roles in various biological processes. Its pharmacological actions are primarily associated with its role as a coenzyme in cellular functions:
1.Nerve Regeneration and Repair: Mecobalamin supports the regeneration and repair of damaged nerve cells. It is actively involved in the synthesis of nucleic acids, promoting the repair and regeneration of axonal nerves and enhancing nerve function.
2.Hematological Function: Mecobalamin is essential for erythropoiesis, the process of producing red blood cells, thereby preventing megaloblastic anemia. It supports the methylation of homocysteine to methionine, essential for DNA synthesis and red blood cell formation.
3.Neurological Benefits: It is used in the treatment of neuropathies, including diabetic neuropathy and other peripheral nerve disorders, by improving the electrophysiological parameters of neurons and enhancing the myelination of neurons.
4.Cognitive Function: Mecobalamin may aid in improving cognitive and emotional functions. Its role in the synthesis of neurotransmitters can potentially benefit patients with cognitive and mood disorders.
5.Methyl Donor: As a methyl donor, Mecobalamin participates in methylation reactions crucial for DNA synthesis and repair, and the metabolism of various neurotransmitters.
6.Energy Metabolism: It supports energy metabolism by facilitating the conversion of proteins, fats, and carbohydrates into usable energy through its role in the Citric Acid Cycle.
