Solubility: Slightly soluble in water, soluble in methanol, slightly soluble in ethanol (96%)
pKa: 9.45 (at 25°C)
Stability: Solutions degrade rapidly at pH 11-13, are sensitive to light, and it is recommended to freshly prepare solutions and protect them from light.
Safety Information
Hazard Statements: Harmful if inhaled, in contact with skin, or if swallowed.
Precautionary Statements: Wear suitable protective clothing, gloves, and eye/face protection; Do not breathe dust.
Safety Phrases: S22 (Do not breathe dust.); S36/37/39 (Wear suitable protective clothing, gloves, and eye/face protection.)
Risk Phrases: R20/21/22 (Harmful by inhalation, in contact with skin, and if swallowed.)
Applications
Dobutamine Hydrochloride is an active pharmaceutical ingredient belonging to vasoactive drugs for anti-shock treatment.
Clinically used for heart failure with low cardiac output and slow heart rate, it is superior to dopamine in improving left ventricular function.
Storage Conditions
Store in a well-closed container, protected from light, and at a temperature of 2-8°C.
Precautions
Dobutamine Hydrochloride is chemically unstable, susceptible to degradation, oxidation, and destruction by air, light, heat, trace amounts of metals such as copper and iron, and pH.