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Dobutamine Hydrochloride
    Publish time 2024-09-26 17:15    

CAS NO.: 49745-95-1

Dobutamine Hydrochloride

Basic Information

  • Chinese Name: 盐酸多巴酚丁胺

  • English Name: Dobutamine Hydrochloride

  • CAS Number: 49745-95-1

  • EINECS Number: 256-464-1

  • Molecular Formula: C18H23NO3·HCl

  • Molecular Weight: 337.84 (or 337.85)

Physical and Chemical Properties

  • Melting Point: 184-186°C

  • Solubility: Slightly soluble in water, soluble in methanol, slightly soluble in ethanol (96%)

  • pKa: 9.45 (at 25°C)

  • Stability: Solutions degrade rapidly at pH 11-13, are sensitive to light, and it is recommended to freshly prepare solutions and protect them from light.

Safety Information

  • Hazard Statements: Harmful if inhaled, in contact with skin, or if swallowed.

  • Precautionary Statements: Wear suitable protective clothing, gloves, and eye/face protection; Do not breathe dust.

  • Safety Phrases: S22 (Do not breathe dust.); S36/37/39 (Wear suitable protective clothing, gloves, and eye/face protection.)

  • Risk Phrases: R20/21/22 (Harmful by inhalation, in contact with skin, and if swallowed.)

Applications

  • Dobutamine Hydrochloride is an active pharmaceutical ingredient belonging to vasoactive drugs for anti-shock treatment.

  • Clinically used for heart failure with low cardiac output and slow heart rate, it is superior to dopamine in improving left ventricular function.

Storage Conditions

  • Store in a well-closed container, protected from light, and at a temperature of 2-8°C.

Precautions

  • Dobutamine Hydrochloride is chemically unstable, susceptible to degradation, oxidation, and destruction by air, light, heat, trace amounts of metals such as copper and iron, and pH.