@
placement:
NameDescriptionContent
Product Showcase
Azilsartan
    Publish time 2024-09-26 16:30    

CAS NO.: 147403-03-0

Azilsartan

Basic Information

  • Chinese Name: Azilsartan

  • English Name: Azilsartan

  • Synonyms: 2-Ethoxy-1-[[2'-(4,5-dihydro-5-oxo-1,2,4-oxadiazol-3-yl)biphenyl-4-yl]methyl]benzimidazole-7-carboxylic acid

  • CAS Number: 147403-03-0

  • Molecular Formula: C25H20N4O5

  • Molecular Weight: 456.45 (Note: slight variations may exist in different sources but are generally close)

Physical and Chemical Properties

  • Melting Point: 188°C (decomposes)

  • Density: 1.42

  • Solubility: Soluble in DMSO at 15 mg/mL (clear solution), slightly soluble in methanol, very slightly soluble in ethanol

Uses

Azilsartan is a drug under development for the treatment of hypertension as an angiotensin II receptor antagonist. It is currently the only angiotensin II receptor antagonist (sartan class) drug in late-stage clinical development. It was approved for marketing in Japan on January 18, 2012, and has obtained marketing authorization in the United States and the European Union.

Safety and Storage

  • Hazard Description: Specific acute toxicity data is not provided, but it should be considered a potentially hazardous substance, and chemical safety operating procedures should be followed.

  • Storage Conditions: Should be stored under refrigerated conditions at 2-8°C, away from incompatible materials such as oxidizers, and kept in tightly closed containers.

Precautions

  • When handling azilsartan, wear appropriate personal protective equipment such as protective gloves, safety goggles, and dust masks.

  • Avoid direct contact with skin, eyes, and clothing. If contact occurs, immediately flush with copious amounts of water and seek medical attention.

  • Comply with relevant chemical safety management and use regulations.