Clindamycin Hydrochloride is a semisynthetic lincosamide antibiotic.
Basic Information
English Name: Clindamycin Hydrochloride
CAS Registry Number: 21462-39-5
Molecular Formula: C18H34Cl2N2O5S
Molecular Weight: 461.44
Pharmacological Action
Clindamycin Hydrochloride exerts its antibacterial effect by inhibiting bacterial protein synthesis through its action on the 50S subunit of bacterial ribosomes. Its antibacterial spectrum is similar to that of lincomycin, but it exhibits stronger antibacterial activity.
Indications
Clindamycin Hydrochloride is indicated for the following infections caused by sensitive strains such as Streptococcus, Staphylococcus, and anaerobes: otitis media, sinusitis, suppurative tonsillitis, pneumonia; skin and soft tissue infections; and can be used alone or in combination with other antibiotics for the treatment of bone and joint infections, intra-abdominal infections, pelvic infections, empyema, lung abscess, osteomyelitis, sepsis, and other diseases as appropriate.
