Molecular Formula: May vary slightly depending on sources, but commonly C54H92N10O17 (or as mentioned in some literature, C52H88N10O15·2C2H4O2)
Molecular Weight: 1153.38
Physical Properties
Appearance: White or off-white lyophilized cake/white powder (depending on product form)
Solubility: Practically insoluble in water but soluble in methanol, dimethyl sulfoxide, and strong alkaline solutions
Chemical Properties
Class: Echinocandin antifungal agent
Mechanism of Action: Inhibits the synthesis of β-(1,3)-D-glucan, an essential component of the fungal cell wall, by inhibiting the enzyme glucan synthase, leading to disruption of the fungal cell wall and ultimately cell death
Pharmacological Effects
Indications:
Empirical therapy for presumed fungal infections in febrile, neutropenic patients
Treatment of invasive aspergillosis in patients who are refractory to or intolerant of other therapy
Antifungal Spectrum: Exhibits in vitro activity against Aspergillus species (including Aspergillus fumigatus, Aspergillus flavus, Aspergillus niger, etc.) and Candida species (including Candida albicans, Candida dubliniensis, Candida glabrata, etc.)
