Chlorphenamine Maleate is a commonly used anti-allergic medication.
Basic Information
English Name: Chlorphenamine Maleate
CAS NO: 113-92-8
Molecular Formula: C20H23ClN2O4
Molecular Weight: 390.86
Pharmacological Action
Chlorphenamine Maleate acts as an antagonist of histamine H1 receptors, primarily exhibiting anti-allergic effects. It counteracts the histamine-induced dilation of blood vessels, reduces capillary permeability, and alleviates bronchoconstriction caused by allergic reactions. This medication exhibits prolonged antihistaminic effects and also has notable central nervous system depressant properties, enhancing the effects of anesthetics, analgesics, hypnotics, and local anesthetics.
Indications
Chlorphenamine Maleate is indicated for various skin allergies, including urticaria, eczema, dermatitis, drug eruptions, pruritus, neurodermatitis, insect bites, solar dermatitis, etc. It is also used to treat symptoms of allergic rhinitis, drug allergies, food allergies, and more.