Etodolac

Etodolac is a nonsteroidal anti-inflammatory drug (NSAID) primarily used to relieve the symptoms and signs of rheumatoid arthritis, osteoarthritis, and mild to moderate pain. 

Basic Information

• Generic Name: Etodolac

• Chemical Formula: C17H21NO3

• Molecular Weight: 287.36

• CAS Number: 41340-25-4

Pharmacological Action

Etodolac exerts its anti-inflammatory, analgesic, and antipyretic effects by inhibiting the activity of cyclooxygenase-2 (COX-2), thereby reducing the synthesis of prostaglandins at inflammatory sites. Compared to cyclooxygenase-1 (COX-1), Etodolac exhibits greater selectivity towards COX-2, resulting in relatively fewer gastrointestinal adverse effects.

Indications

• Relief of symptoms and signs of rheumatoid arthritis and osteoarthritis.

• Management of mild to moderate pain.

• Postoperative pain treatment.