Loxoprofen Sodium is a non-steroidal anti-inflammatory drug (NSAID) that possesses analgesic, anti-inflammatory, and antipyretic effects.
I. Basic Information
English Name: Loxoprofen Sodium
Chemical Formula: C15H17NaO3
Molecular Weight: 268.28
CAS Registry Number: 80382-23-6
II. Pharmacological Action
As a prodrug, Loxoprofen Sodium is converted into an active metabolite after absorption in the digestive tract. Its active metabolite exerts analgesic, anti-inflammatory, and antipyretic effects by inhibiting the synthesis of prostaglandins.
III. Indications
Loxoprofen Sodium is widely used clinically in the following conditions:
Anti-inflammatory and analgesic effects for rheumatoid arthritis, degenerative joint disease, lumbago, periarthritis of the shoulder, and cervical-shoulder-arm syndrome.
Analgesic and anti-inflammatory effects after surgery, trauma, and tooth extraction.
Antipyretic and analgesic effects for acute upper respiratory tract infections (including acute upper respiratory tract infections with acute bronchitis).