Carboprost Tromethamine, also known as carboprost tromethamine, is a widely used medication in medical fields, particularly in gynecology and obstetrics.
Basic Information
English Name: Carboprost Tromethamine
CAS Number: 58551-69-2
Molecular Formula: C25H47NO8
Molecular Weight: 489.65
Indications
Primarily used to promote regular uterine contractions and significantly reduce postpartum bleeding.
Used for second trimester abortion.
Used for postpartum hemorrhage caused by atonic uterus that is unresponsive to conventional treatments.
Pharmacological Action
Carboprost Tromethamine is a 15-methyl analog of prostaglandin F2α (PGF2α), which effectively promotes regular uterine contractions and significantly reduces postpartum bleeding. Its mechanism of action may involve facilitating the formation of gap junctions between uterine smooth muscle cells, enhancing the frequency and amplitude of uterine contractions.
