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Milrinone
    Publish time 2024-09-20 16:26    

CAS NO.: 78415-72-2

Milrinone

I. Basic Information

  • Chinese Name: 米力农

  • English Name: Milrinone

  • CAS Number: 78415-72-2

  • Molecular Formula: C12H9N3O

  • Molecular Weight: 211.22

  • EINECS Number: 278-903-6

II. Physical Properties

  • Density: Approximately 1.3±0.1 g/cm³

  • Melting Point: >300°C (some sources indicate 313-316°C)

  • Boiling Point: 448.7±45.0 °C at 760 mmHg

  • Flash Point: 225.2±28.7 °C

  • Solubility: Soluble in organic solvents such as DMSO, insoluble in water

III. Chemical Properties

  • Stability: Stable under normal temperature and pressure, keep away from oxidizers

  • Storage Conditions: Store in a sealed container at 2-8°C

IV. Uses

  • Milrinone is a medication used in the treatment of cardiac insufficiency. It enhances myocardial contractility and directly dilates blood vessels.

  • As a PDE3 inhibitor, it inhibits the degradation of cAMP, thereby increasing myocardial contractility.

  • It is primarily used in the treatment of severe heart failure conditions such as chronic heart failure and congestive heart failure.

V. Safety Information

  • Hazard Symbol: GHS06

  • Signal Word: Danger

  • Risk Phrase(s): R23/24/25

  • Safety Phrase(s): S36/37/39; S45

  • UN Number for Transport of Dangerous Goods: UN 2811

  • Personal Protective Equipment: Recommended to wear protective eyewear, face shield, gloves, and P2 respirator