Basic Information

• Chinese Name: 依贝沙坦

• English Name: Irbesartan

• CAS Number: 138402-11-6

• Molecular Formula: C25H28N6O

• Molecular Weight: 428.52942

Physical Properties

• Appearance: White crystalline powder or white powder

• Melting Point: 180-181°C (may vary depending on sources, another source indicates 185.0 to 190.0°C)

• Boiling Point: 648.6°C at 760 mmHg

• Flash Point: 346°C

• Density: 1.3 g/cm³

• Refractive Index: 1.689

Chemical Properties

• An angiotensin II receptor antagonist belonging to the angiotensin II type 1 (AT1) receptor blockers.

• Interacts with angiotensin II receptors in vascular smooth muscle, leading to relaxation of the smooth muscle and subsequent dilation of the peripheral arterioles and reduction of blood pressure.

Uses

• Used in the treatment of hypertension, as an antihypertensive agent.

• May also be used in the study of heart failure and diabetic nephropathy.

Safety Information

• RTECS Number: HM2950270

• WGK Germany: 3

• Safety Phrases: S26, S36/37/39

• Risk Phrases: R22

• Hazard Symbols: Xn

• UN Number for Transport of Dangerous Goods: 3276