Molecular Weight: 346.33~346.34 (may vary slightly from different sources)
EINECS Number: 244-598-3
Physical Properties
Appearance and Odor: Yellow crystalline powder or solid, odorless, tasteless
Density: 1.271 g/cm³
Melting Point: 171-175°C (may vary slightly from different sources)
Boiling Point: 475.3°C at 760 mmHg
Flash Point: 241.2°C
Solubility: Easily soluble in acetone or chloroform, slightly soluble in ethanol, practically insoluble in water
Chemical Properties
Nifedipine is a cardiovascular drug primarily used in the treatment of various acute and chronic coronary insufficiencies, angina pectoris, and other conditions. It works by inhibiting the membrane transport of calcium ions in cardiac and vascular smooth muscle, thus inhibiting the influx of calcium ions into cells. This leads to reduced myocardial contractility and vasodilation, ultimately lowering blood pressure and relieving angina symptoms.
Uses
Uses: Nifedipine has a wide range of clinical applications as a cardiovascular drug. It can be used alone or in combination with other drugs to achieve better therapeutic effects.
Storage Conditions
Nifedipine should be stored in a cool, dry, well-ventilated place, away from fire and heat sources. It should also be protected from direct sunlight and moisture to prevent deterioration or loss of potency.