Mometasone Furoate is a synthetic glucocorticoid medication that possesses various pharmacological effects including anti-inflammatory, anti-allergic, antipruritic, and vasoconstrictive properties.
Basic Information
English Name: Mometasone Furoate
CAS Number: 83919-23-7
Molecular Formula: C27H30Cl2O6
Molecular Weight: 521.43
Pharmacological Effects
As a moderately potent corticosteroid, Mometasone Furoate effectively alleviates inflammation, itching, and other symptoms when applied topically to the skin. Its unique molecular structure, featuring a C1,2 double bond and C9,21 chlorination, enhances its anti-inflammatory activity and lipophilicity, allowing for rapid skin penetration and potent local therapeutic effects while minimizing systemic absorption and reducing the risk of adverse reactions.
Clinical Applications
Mometasone Furoate is primarily used to treat skin conditions that respond favorably to corticosteroid therapy, such as neurodermatitis, eczema, atopic dermatitis, and other inflammatory skin disorders causing itching and irritation. Widely employed in dermatology, it is favored by both physicians and patients for its high efficacy and low incidence of adverse effects.
