Dexamethasone is a synthetic, long-acting glucocorticoid medication that exhibits significant anti-inflammatory, anti-endotoxin, and immunosuppressive pharmacological effects.
Basic Information
English Name: Dexamethasone
CAS Number: 50-02-2
Molecular Formula: C22H29FO5
Type of Drug: Long-acting glucocorticoid
Pharmacological Effects
Anti-inflammatory: Reduces inflammation, alleviating symptoms such as redness, swelling, heat, and pain.
Anti-endotoxin: Offers some resistance to endogenous toxins.
Immunosuppression: Suppresses excessive immune system reactions, thereby reducing tissue damage.
Anti-shock and Enhanced Stress Response: Enhances the body's ability to respond to stress situations such as shock.
Indications
Dexamethasone is primarily used to treat allergic and autoimmune inflammatory diseases, including but not limited to:
Connective tissue diseases
Severe bronchial asthma
Dermatitis and other allergic conditions
Ulcerative colitis
Acute leukemia
Malignant lymphoma
Additionally, Dexamethasone is used for diagnostic purposes in certain adrenal cortical diseases, such as the dexamethasone suppression test.