Amoxicillin is an organic compound with the chemical formula C16H19N3O5S, belonging to the class of broad-spectrum penicillin antibiotics.
Basic Information
Chemical Name: Amoxicillin
English Name: Amoxicillin
Chemical Formula: C16H19N3O5S
Molecular Weight: 365.404
CAS Registry Number: 26787-78-0
EINECS Number: 248-003-8
Physical Properties
Appearance: Light yellow solid
Melting Point: Approximately 140°C (specific values may vary depending on measurement conditions)
Boiling Point: 701.8°C (predicted value)
Density: 1.54 g/cm³ (or 1.6±0.1 g/cm³, with slight variations in data from different sources)
Flash Point: 378.2°C (or 403.3°C, with slight variations in data from different sources)
Solubility in Water: 4 g/L (at 25°C)
Pharmacological Action
Amoxicillin inhibits the biosynthesis of bacterial cell walls, leading to wall defects, cell swelling, and ultimately lysis, thereby exerting its bactericidal and bacteriostatic effects.
It exhibits strong antibacterial activity against various Gram-positive and Gram-negative bacteria, including streptococci, pneumococci, staphylococci, influenzae, Escherichia coli, etc.
Indications
Amoxicillin is primarily used to treat infections caused by susceptible bacteria, including:
Respiratory infections: such as acute otitis media, streptococcal pharyngitis, pneumonia, etc.
Urinary tract infections: such as cystitis, urethritis, etc.
Gastrointestinal infections: such as bacterial gastroenteritis, bacillary dysentery, etc.
Skin and soft tissue infections: such as furuncles, carbuncles, abscesses, etc.
