I. Basic Information

• product Name: Exemestane

• CAS Number: 107868-30-4

• Molecular Formula: C20H24O2

• Molecular Weight: 296.403

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II. Physical Properties

• Appearance: White to pale yellow crystalline powder

• Density: 1.13 g/cm³ (alternatively, 1.1±0.1 g/cm³, depending on sources)

• Melting Point: 155.1ºC (alternatively, 155.13°C, according to specific data)

• Boiling Point: 453.7ºC

• Flash Point: 169ºC (alternatively, 169.0±25.7 °C, depending on sources)

• Solubility: Soluble in methanol, insoluble in water

III. Pharmaceutical Characteristics

• Category: Antineoplastic agent, second-generation aromatase inhibitor

• Mechanism of Action: Irreversible steroidal aromatase inactivator that blocks the activity of aromatase, thereby preventing the production of estrogens and reducing circulating estrogen levels

• Indications: Clinically indicated for postmenopausal women with advanced breast cancer who have progressed following tamoxifen therapy