Solubility: Insoluble in water, slightly soluble in methanol, very slightly soluble in ethanol, insoluble in ether
Chemical Properties
Cefditoren Pivoxil is a broad-spectrum third-generation oral cephalosporin antibacterial agent with enhanced stability against various common β-lactamases.
Cefditoren Pivoxil exhibits activity against both Gram-negative and Gram-positive bacteria, including Staphylococcus aureus, Streptococcus pneumoniae, Escherichia coli, Klebsiella pneumoniae, Proteus species, and others.
Uses and Efficacy
Cefditoren Pivoxil is used in research for infectious diseases such as acute exacerbations of chronic bronchitis, community-acquired pneumonia (CAP), streptococcal pharyngitis/tonsillitis, or uncomplicated skin and skin structure infections.
After absorption, Cefditoren Pivoxil is hydrolyzed by esterases in the intestinal wall to generate cefditoren, which exerts its antibacterial effect.
Safety Information
Cefditoren Pivoxil is generally stable but should be avoided from contact with oxidizing agents and other substances.
Regarding toxicity information, acute toxicity experiments have shown that the oral median lethal dose (LD50) in rats is greater than 5100 mg/kg, indicating relatively low acute toxicity.
In summary, Cefditoren Pivoxil is a third-generation oral cephalosporin antibacterial agent with broad-spectrum antibacterial activity, stable chemical properties, and good therapeutic effects. When using it, medical advice should be followed, and the instructions should be strictly adhered to.
