1.Inhibition of Gastric Acid Secretion: Esomeprazole Sodium works as a proton pump inhibitor (PPI) by inhibiting the H+/K+ ATPase enzyme in the parietal cells of the stomach. This action blocks the final step in the production of gastric acid, leading to a significant reduction in acid secretion both in the basal and stimulated state.
2.Treatment of Gastroesophageal Reflux Disease (GERD): By reducing gastric acid production, Esomeprazole Sodium provides relief from symptoms of GERD including heartburn and esophagitis, thereby improving patient quality of life and allowing healing of the esophageal lining.
3.Peptic Ulcers: Esomeprazole Sodium is effective in treating peptic ulcers, including those caused by Helicobacter pylori infection. It is often used in combination with antibiotics to eradicate the bacteria and reduce the risk of ulcer recurrence.
4.Zollinger-Ellison Syndrome: This drug is also used to manage conditions involving excessive gastric acid production, such as Zollinger-Ellison syndrome, providing effective control over acid secretion.
5.Protection Against NSAID-Induced Gastric Damage: For patients on long-term nonsteroidal anti-inflammatory drugs (NSAIDs), Esomeprazole Sodium can be prescribed to prevent gastric ulcers and erosions associated with NSAID use.
