Smooth Muscle Relaxant: Drotaverine Hydrochloride is a potent smooth muscle relaxant. It inhibits phosphodiesterase-IV enzyme, leading to an increase in cyclic adenosine monophosphate (cAMP) levels in smooth muscle cells, which in turn causes muscle relaxation.
Antispasmodic Effect: It is commonly used to relieve spasms and pain in various conditions involving smooth muscles, such as gastrointestinal, urinary, biliary, and uterine cramps.
Analgesic Overview: Drotaverine also has moderate analgesic properties, providing relief from pain associated with spasmodic conditions.
Vasodilation: By relaxing smooth muscle in blood vessel walls, Drotaverine can cause vasodilation, which can improve blood flow and, subsequently, oxygen supply to cells and tissues.
Gastrointestinal Actions: It alleviates spasms of the gastrointestinal tract in conditions like irritable bowel syndrome, colitis, and enterocolitis.
Gynecological Use: It is often prescribed for dysmenorrhea (painful menstruation) and to relieve labor pains due to its ability to relax uterine muscles.
