English Name: 2-(3-hydroxypropoxy)-1,25-dihydroxyvitamin D3
Molecular Formula: C30H50O5
Molecular Weight: 490.725 g/mol
CAS Number: 104121-92-8
Pharmacological Effects
1.Enhancing Calcium Absorption: Eldecalcitol increases calcium absorption in the small intestine by promoting the synthesis of calcium-binding proteins, thereby improving the efficiency of calcium ion transport.
2.Promoting Bone Mineralization: It helps maintain the bone mineralization process by promoting the mechanisms of calcium deposition in the bone matrix, which contributes to bone strength and resilience.
3.Inhibiting Bone Resorption: By regulating the activity of osteoclasts in bone metabolism, Eldecalcitol can slow down and inhibit the bone resorption process, helping to reduce bone loss.
4.Regulating Calcium and Phosphorus Metabolism: Eldecalcitol balances the metabolism of calcium and phosphorus in the body, maintaining normal concentrations of serum calcium and phosphorus. This balance is crucial for bone health and the proper functioning of various physiological processes.
5.Suppressing Parathyroid Hormone: Eldecalcitol can indirectly promote bone health by regulating and inhibiting the secretion of parathyroid hormone (PTH). Elevated PTH levels can lead to bone calcium loss, and by suppressing its secretion, Eldecalcitol helps protect bone density.
