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Atropine sulphate
    Publish time 2024-09-27 16:18    

CAS No.: 55-48-1

Atropine sulphate

Basic Information:

  • English Name: Atropine Sulfate

  • CAS Number: 55-48-1

  • Molecular Formula: C34H48N2O10S

  • Molecular Weight: 676.822 g/mol

  • Synonyms: Atropine monohydrate sulfate, Atropine methosulfate

Pharmacological Action:

  • Mechanism of Action: Atropine sulfate is a highly selective antagonist of muscarinic acetylcholine receptors (mAChRs). It inhibits the action of acetylcholine at the parasympathetic  sites in smooth muscle, secretory glands, and the central nervous system  (CNS).

  • Effects on the Body:

    • Cardiovascular: Increases heart rate by blocking vagal  effects on the heart (tachycardia).

    • Gastrointestinal: Reduces motility and secretion of the stomach and intestines.

    • Respiratory: Bronchodilation and reduced secretion in the respiratory tract.

    • Ophthalmic: Dilation of the pupil (mydriasis) and paralysis of the lens (cycloplegia).

    • Central Nervous System: Depending on the dose, it can lead to mild stimulation of the CNS or, at higher doses, restlessness, disorientation, hallucinations, or even delirium.