Mechanism of Action: Atropine sulfate is a highly selective antagonist of muscarinic acetylcholine receptors (mAChRs). It inhibits the action of acetylcholine at the parasympathetic sites in smooth muscle, secretory glands, and the central nervous system (CNS).
Effects on the Body:
Cardiovascular: Increases heart rate by blocking vagal effects on the heart (tachycardia).
Gastrointestinal: Reduces motility and secretion of the stomach and intestines.
Respiratory: Bronchodilation and reduced secretion in the respiratory tract.
Ophthalmic: Dilation of the pupil (mydriasis) and paralysis of the lens (cycloplegia).
Central Nervous System: Depending on the dose, it can lead to mild stimulation of the CNS or, at higher doses, restlessness, disorientation, hallucinations, or even delirium.