Mechanism of Action: Perospirone Hydrochloride is a second-generation atypical antipsychotic. It primarily functions as a dopamine D2 receptor antagonist and a serotonin 5-HT2 receptor antagonist. This dual antagonism is thought to contribute to its efficacy in treating psychiatric disorders.
Antipsychotic Effects: By blocking the D2 dopamine receptors, Perospirone Hydrochloride can help mitigate the positive symptoms of schizophrenia, such as delusions and hallucinations. The blockage of 5-HT2 receptors is believed to ameliorate the negative symptoms of schizophrenia and reduce the risk of extrapyramidal side effects compared to first-generation antipsychotics.
Mood Stabilizing Effects: The drug's action on serotonin receptors also imparts mood-stabilizing properties, making it potentially useful for treating disorders involving mood dysregulation.
Other Actions: Additional pharmacological actions may include interactions with α1-adrenergic and histamine H1 receptors, contributing to the overall therapeutic profile and side effect profile of the medication.
