Chemical Name: Brivaracetam CAS Number: 357336-20-0 Molecular Formula: C11H20N2O2 Molecular Weight: 212.29 g/mol
Pharmacological Actions
Brivaracetam is an anticonvulsant or anti-epileptic drug that exhibits its effects through several mechanisms:
1.Binding to SV2A Vesicle Protein: Brivaracetam selectively binds to synaptic vesicle protein 2A (SV2A), which is involved in the regulation of neurotransmitter release. This binding modulates the release of neurotransmitters, contributing to its anti-seizure effects.
2.Inhibition of Voltage-Gated Sodium Channels: The drug inhibits voltage-gated sodium channels, which are crucial for the propagation of action potentials in neurons. By stabilizing the inactive state of these channels, Brivaracetam helps reduce the hyperexcitability of neurons associated with epileptic activity.
3.Anticonvulsant Properties: Brivaracetam has shown efficacy in reducing the frequency and severity of seizures in patients suffering from epilepsy.
