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Rasagiline Mesylate
    Publish time 2024-09-27 15:10    

CAS No.: 161735-79-1

Rasagiline Mesylate

1. Basic Information
- English Name: Rasagiline Mesylate
- CAS Number: 161735-79-1
- Molecular Formula: C12H13N•CH4O3S
- Molecular Weight: 267.343 g/mol

2. Pharmacological Action
Rasagiline Mesylate is a selective, irreversible monoamine oxidase-B (MAO-B) inhibitor. It is widely used in the treatment of Parkinson's disease due to its pharmacological properties. Here are a few key actions:

  • Inhibition of MAO-B Enzyme: By irreversibly inhibiting the MAO-B enzyme, Rasagiline increases the levels of dopamine  in the brain. This helps alleviate the motor symptoms associated with Parkinson's disease.

  • Neuroprotective Effects: Rasagiline has been observed to have neuroprotective properties, which may help in protecting the neurons from various types of damage, including oxidative stress.

  • Improved Functional Status: It may contribute to  improved motor function and reduce the wearing-off phenomena in patients  treated with levodopa.

  • Reduction of Oxidative Stress: As an MAO-B inhibitor,  Rasagiline helps in decreasing the production of hydrogen peroxide and other harmful substances that can contribute to neuronal damage.