Lurasidone Hydrochloride is an atypical antipsychotic with several pharmacological effects:
Serotonin-Dopamine Antagonist: Primarily acts as an antagonist at the dopamine D2 and serotonin 5-HT2A receptors. This dual antagonism is associated with its antipsychotic effects.
Serotonin 5-HT7 and 5-HT1A Effects: It exhibits antagonistic activity at the 5-HT7 receptor and is a partial agonist at the 5-HT1A receptor.
Adrenergic and Histaminergic Receptors: Has minimal affinity for adrenergic receptors and histamine H1 receptors, potentially reducing the risk of certain side effects seen with other antipsychotics, such as orthostatic hypotension and sedation.
Mood Stabilization: This medication may also have mood-stabilizing properties, making it useful for the treatment of bipolar depression.
Cognitive Function Improvement: Some studies suggest that Lurasidone may improve certain cognitive functions, possibly due to its receptor profile and effects on neurotransmitter pathways.
