Basic Information

• CAS Number: 313348-27-5

• English Name: Regadenoson

• Chinese Name: 瑞加诺生

• Molecular Formula: C15H18N8O5

• Molecular Weight: 390.354 g/mol

• Density: Approximately 2.0±0.1 g/cm³

• Melting Point: 158-160ºC

• Storage Conditions: Typically stored at -20°C. Although it has a long shelf life, it is recommended to use the solution as soon as possible (within a month) after dissolution.

Physical and Chemical Properties

• PSA: 186.46000 Ų

• LogP: -3.09

• Refractive Index: 1.896

• Solubility: Varies in different solvents. For example, it has low solubility in water (<1 mg/ml), high solubility in DMSO (4 mg/ml), and low solubility in ethanol (<1 mg/ml).

Uses and Efficacy

REGADENOSON is an A2A adenosine receptor agonist primarily used in scientific research, particularly in the field of cardiovascular disease. Pharmacologically, it serves as a pharmacological stress agent for radionuclide myocardial perfusion imaging (MPI) in patients unable to undergo adequate exercise stress. Compared to adenosine, which is also commonly used for cardiac stress testing, REGADENOSON does not cause bronchoconstriction or atrioventricular block, exhibits significant effects, and has fewer adverse reactions.