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Bezafibrate
    Publish time 2024-09-26 17:41    

CAS NO.: 41859-67-0

Bezafibrate

Basic Information:

  • Chinese Name: 苯扎贝特

  • English Name: Bezafibrate    

  • CAS Number: 41859-67-0

  • EINECS Number: 255-567-9

  • Molecular Formula: C19H20ClNO4

  • Molecular Weight: 361.822 (or 361.8194, slight variations may exist depending on sources)

Physical Properties:

  • Density: 1.26 g/cm³

  • Melting Point: 184°C

  • Boiling Point: 572.1°C at 760 mmHg

  • Flash Point: 299.8°C

  • Vapor Pressure: 0.0±1.7 mmHg at 25°C (or 6.29E-14 mmHg at 25°C, slight variations may exist depending on sources)

  • Solubility: Slightly soluble in water

Chemical Properties:

  • Acid Dissociation Constant (pKa): 3.29±0.10 (Predicted)

  • Stability: Stable under specified storage conditions

Uses:

  • Bezafibrate is a fibrate class of hypolipidemic drug with antithrombotic effects.

  • It acts as a PPAR agonist, exhibiting varying EC50 values for PPARα, PPARγ, and PPARδ in humans and rats, demonstrating hypolipidemic activity.

Safety Information:

  • Hazard Symbol: Xn (Harmful)

  • Risk Phrases: R22 (Harmful if inhaled)

  • Safety Phrases: S36 (Wear suitable protective clothing)

Storage Conditions:

  • Store in a sealed, cool, and dry place.