Chemical Name: Pramipexole Dihydrochloride Monohydrate
Molecular Formula: C10H17N3S·2HCl·H2O
Molecular Weight: 302.24 g/mol
CAS Number: 191217-81-9
Pharmacological Action
Drug Type: Pramipexole dihydrochloride monohydrate is a non-ergoline dopamine agonist. It is commonly used in the treatment of Parkinson's disease and Restless Legs Syndrome (RLS).
Mechanism of Action: Pramipexole works by stimulating dopamine receptors in the brain, particularly the D2 and D3 receptors. Dopamine is a neurotransmitter that is crucial for coordinating smooth and balanced muscle movements. In Parkinson's disease, the levels of dopamine are significantly reduced, leading to motor symptoms such as tremor, rigidity, and bradykinesia. By directly activating dopamine receptors, pramipexole helps to restore the balance of dopamine in the brain, thus alleviating these symptoms.