@
placement:
NameDescriptionContent
Product Showcase
Adenosine
    Publish time 2024-09-26 17:04    

CAS NO.: 58-61-7

Adenosine

Basic Information

  • Chinese Name: 腺苷

  • English Name: Adenosine

  • CAS Number: 58-61-7

  • Molecular Formula: C10H13N5O4

  • Molecular Weight: 267.24

Physical and Chemical Properties

  • Melting Point: 234-236°C

  • Boiling Point: 676.3°C at 760 mmHg

  • Density: 2.08 g/cm³

  • Solubility: Slightly soluble in water, soluble in hot water, practically insoluble in ethanol (96%) and dichloromethane, but soluble in dilute mineral acids and dimethyl sulfoxide

  • Specific Rotation: [-61.7° (C=0.706, water); -58.2° (C=0.658, water)]

Uses

  1. Biochemistry: Adenosine is an important endogenous nucleoside in living organisms. It can directly enter cardiomyocytes and be phosphorylated to generate adenosine monophosphate (AMP), participating in myocardial energy metabolism. It also contributes to dilating coronary vessels and increasing blood flow.

  2. Pharmaceuticals:

    • Used in the treatment of cardiovascular diseases such as angina pectoris, myocardial infarction, and coronary insufficiency.

    • Has antiarrhythmic effects, converting paroxysmal supraventricular tachycardia to sinus rhythm.

    • Used in the treatment of arteriosclerosis, essential hypertension, cerebrovascular disorders, sequelae of stroke, and progressive muscular atrophy.

  3. Biochemical Research: Acts as an essential raw material for scientific research, used in the synthesis of adenosine triphosphate (ATP), adenine, adenosine acid, and arabinosyladenine.

Storage and Transportation

  • Storage: Should be stored in a cool, dry place, protected from direct sunlight, with a temperature controlled at 2-8°C.

  • Transportation: Typically shipped via express delivery or logistics. Domestic express delivery usually arrives within three days, while logistics takes approximately five days.

Safety Information

  • Respiratory Protection: Respiratory protection is generally not required when handling adenosine. However, for dust protection, N95 (US) or P1 (EN143) dust masks can be used.

  • Environmental Hazards: According to international transportation regulations, adenosine is classified as a non-hazardous material.