Mechanism of Action: - Risperidone is an atypical antipsychotic medication. It works by modulating the effects of various neurotransmitters in the brain, particularly dopamine and serotonin (5-HT). - It acts as an antagonist at dopamine D2 receptors and serotonin 5-HT2A receptors. This means it blocks the action of dopamine and serotonin at these receptor sites. It also has antagonistic effects on alpha-adrenergic receptors and, to a lesser extent, histamine H1 receptors.
Key Uses: - Schizophrenia: Risperidone is commonly used to treat schizophrenia, helping to reduce symptoms such as delusions, hallucinations, and thought disturbances. - Bipolar Disorder: It is used to manage acute manic or mixed episodes associated with bipolar disorder. - Irritability in Autism: In pediatric patients, it can help manage irritability and aggression associated with autism.