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Pravastatin Sodium
    Publish time 2024-09-25 18:25    

CAS NO.: 81131-70-6

Pravastatin Sodium

Basic Information

  • Chinese Name: 普伐他汀钠

  • English Name: Pravastatin Sodium

  • CAS Number: 81131-70-6

  • Molecular Formula: C23H35NaO7

  • Molecular Weight: 446.51 (Alternatively, 446.50957 or 446.5096, differences stemming from calculation precision)

  • EINECS Number: 617-202-5

Chemical Structure

The chemical structure of Pravastatin Sodium is complex, with the "sodium" part indicating the presence of a sodium ion. The International Union of Pure and Applied Chemistry (IUPAC) name can be lengthy and intricate, but the core would include a description akin to "sodium salt of 1,2,6,7,8,8a-hexahydro-2-methyl-8-(2-methylbutyryloxy)-1-naphthalene-3',5',6-trihydroxyheptanoate" or a similar representation.

Physical Properties

  • Melting Point: Depending on sources, the melting point range varies from 154-160°C to 171.2-173°C, which can be attributed to sample purity and testing conditions.

  • Boiling Point: 634.5°C at 760 mmHg

  • Flash Point: 213.2°C

  • Solubility: Solubility in water is 19 mg/mL (or a similar value, depending on testing conditions).

Uses

Pravastatin Sodium is an essential pharmaceutical intermediate and active pharmaceutical ingredient (API) used primarily in the manufacture of medications for lowering blood lipids and cholesterol. As an HMG-CoA reductase inhibitor, Pravastatin Sodium plays a crucial role in regulating lipid metabolism and preventing and treating cardiovascular diseases.

Safety and Precautions

  • Pravastatin Sodium should be used in accordance with medical advice, avoiding overdosage or improper use.

  • Storage conditions typically involve keeping the product dry, sealed, and refrigerated at 2-10°C to ensure stability and efficacy.

  • During use and storage, avoid contact with substances that may react, such as oxides.