Chemical Name: 2-Methyl-1-[2-(ethylsulfonyl)ethyl]-5-nitro-1H-imidazole
Molecular Formula: C8H13N3O4S
Molecular Weight: 247.27
CAS Registry Number: 19387-91-8
Pharmacological Action:
Tinidazole belongs to the nitroimidazole class of antibiotics and exhibits potent activity against anaerobic bacteria and protozoa, such as Entamoeba histolytica and Trichomonas vaginalis. Its mechanism of action involves inhibiting DNA synthesis of the pathogens and rapidly entering cells. Compared to metronidazole, tinidazole has faster absorption, higher serum concentrations, longer duration of action, and stronger antibacterial activity.
Indications:
Tinidazole is primarily used to treat the following conditions:
Anaerobic sepsis, respiratory infections, intra-abdominal and pelvic infections caused by anaerobic bacteria.
Trichomoniasis, Giardiasis, Amoebiasis, etc.
Urinary and genital trichomoniasis in both males and females.
Various infections caused by sensitive anaerobic bacteria (e.g., Bacteroides fragilis, Peptococcus, Clostridium species) such as pneumonia, lung abscess, endometritis, salpingitis, periodontitis, pericoronitis, etc.
