Basic Chemical Information

• English Name: Trifluridine

• Molecular Formula: C10H11F3N2O5

• Molecular Weight: 296.2 g/mol

• CAS Number: 70-00-8

Pharmacological Action

Therapeutic Effects:
Trifluridine is an antiviral medication used primarily in the treatment of herpes simplex virus infections of the eye. It can be used topically as eye drops to treat keratitis caused by the herpes simplex virus.

Mechanism of Action:
Trifluridine works by incorporating into the viral DNA during replication, causing errors in the viral DNA synthesis. This results in the prevention of the virus from successfully replicating and spreading. Specifically, Trifluridine is a nucleoside analog that inhibits thymidylate synthetase, an enzyme crucial for DNA synthesis.