Basic Chemical Information: - Chemical Name: Baloxavir marboxil - Molecular Formula: C27H23F2N3O7S - Molecular Weight: 571.55 g/mol - CAS Number: 1985606-14-1
Pharmacological Action: Baloxavir marboxil is an antiviral medication primarily used for the treatment of influenza (flu). Its pharmacological actions include:
Inhibition of Cap-dependent Endonuclease: Baloxavir marboxil is a prodrug that is converted into its active form, baloxavir acid, in the body. The active form inhibits the cap-dependent endonuclease activity of the viral polymerase acidic (PA) protein. This inhibition prevents the transcription and replication of the viral RNA, thereby blocking the proliferation of the influenza virus within the host cells.
Reduction of Viral Load: By inhibiting the replication process of the influenza virus, baloxavir marboxil effectively reduces the viral load in the body, leading to a quicker resolution of flu symptoms and a reduced duration of the illness.
