Polaprezinc is a zinc-L-carnosine chelate compound used primarily for its gastrointestinal mucosal protective effects. It acts through several mechanisms:
Mucosal Protection: Polaprezinc forms a complex with gastric mucus, thereby protecting the mucosal lining of the stomach and intestines from damage caused by acid, pepsin, and other irritants. It enhances mucosal resistance and accelerates the repair of damaged mucosal tissue.
Antioxidant Properties: Polaprezinc has antioxidant effects that help in neutralizing reactive oxygen species (ROS), which can damage cellular structures and contribute to inflammatory processes in the gastrointestinal tract.
Anti-inflammatory Effects: It downregulates the expression of inflammatory cytokines and mediates the inflammatory response, which contributes to its protective effects in the gastrointestinal system.
Zinc Supplementation: Zinc is an essential trace element involved in numerous biological processes, including immune function, wound healing, and DNA synthesis. Polaprezinc provides a bioavailable source of zinc, which is crucial for the maintenance and repair of the mucosal lining.
