Ornidazole, also known as a 5-nitroimidazole antibiotic, possesses a broad spectrum of antibacterial activity and is primarily used in the treatment of infectious diseases caused by various sensitive anaerobic bacteria.
Basic Information
English Name: Ornidazole
CAS No.: 16773-42-5
Chemical Name: 1-(3-Chloro-2-hydroxypropyl)-2-methyl-5-nitroimidazole
Molecular Formula: C7H10ClN3O3
Molecular Weight: 219.625
Pharmacological Action
Ornidazole exerts its antibacterial effects by inhibiting bacterial DNA synthesis, thereby halting bacterial growth and reproduction. It demonstrates potent activity against anaerobic bacteria, making it an essential drug in the treatment of anaerobic infections.
Indications
Ornidazole is indicated for a wide range of conditions, including but not limited to:
Anaerobic Infections: Infectious diseases caused by various anaerobic bacteria, such as abdominal infections (peritonitis, intra-abdominal abscesses, liver abscesses, etc.), pelvic infections (endometritis, myometritis, tubo-ovarian abscesses, etc.).
Urogenital Tract Infections: Diseases caused by Trichomonas vaginalis and Giardia lamblia infections, such as trichomoniasis.
Intestinal and Hepatic Infections: Intestinal and hepatic amebiasis (including amebic dysentery, amebic liver abscesses), as well as infections caused by intestinal and hepatic Entamoeba histolytica.
Postoperative Prophylaxis: For prevention and treatment of anaerobic infections after surgical procedures.
