Appearance: White to slightly yellow powder or crystalline powder
Melting Point: 240-245°C (decomposes)
Solubility: Soluble in water and certain organic solvents such as DMSO. Specific solubility data may vary depending on experimental conditions, achieving higher solubility in certain solvent combinations.
III. Chemical Properties
Cefuroxime Sodium is a second-generation cephalosporin antibiotic with broad-spectrum antibacterial activity effective against both Gram-positive and Gram-negative bacteria.
It exhibits increased stability against β-lactamases, enabling it to resist degradation by β-lactamases produced by some bacteria.
IV. Antimicrobial Spectrum
Cefuroxime Sodium demonstrates potent antibacterial activity against a wide range of bacteria, including but not limited to Staphylococcus aureus (S. aureus), methicillin-sensitive S. aureus, methicillin-resistant coagulase-negative staphylococci, Streptococcus pneumoniae (S. pneumoniae), viridans streptococci (S. viridans), Enterococcus faecalis (S. faecalis), and various Gram-negative bacteria.
It exhibits extremely low minimum inhibitory concentrations (MICs) against S. aureus, demonstrating its efficacy, regardless of whether the strain produces penicillinase.
