Metronidazole

Metronidazole, also known as Flagyl, is an antibiotic medication primarily used to treat various infections caused by anaerobic bacteria and protozoa. 

Basic Information

• English Name: Metronidazole

• Chemical Structure: C6H9N3O3

• Molecular Weight: 171.15

• CAS Number: 443-48-1

Pharmacological Action

Metronidazole exhibits potent antibacterial activity against anaerobic bacteria and protozoa, including Trichomonas vaginalis, Entamoeba histolytica, Bacteroides fragilis, Clostridium difficile, and Helicobacter pylori. Its mechanism of action involves inhibiting bacterial deoxyribonucleic acid (DNA) synthesis, thereby disrupting bacterial growth and reproduction.

Indications

Metronidazole is primarily used to treat the following conditions:

• Intestinal and extraintestinal amebiasis

• Trichomoniasis

• Anaerobic infections, such as pseudomembranous colitis, periodontitis, etc.

• Senile vaginitis, trichomoniasis vaginitis, and nonspecific vaginitis (Metronidazole vaginal suppositories)