Naproxen Sodium is an organic compound, primarily used as an antipyretic, analgesic, and nonsteroidal anti-inflammatory drug (NSAID).
Basic Information
English Name: Naproxen Sodium
CAS Number: 26159-34-2
Molecular Weight: 252.24
Molecular formula: C14H13NaO3
Pharmacological Action
Naproxen Sodium exerts a dose-dependent anti-inflammatory, analgesic, and antipyretic effect. Its mechanism of action involves inhibiting cyclooxygenase (COX) activity, thereby inhibiting the synthesis of prostaglandins (PGs). It exhibits stronger selectivity towards COX-2, leading to potent anti-inflammatory effects with relatively fewer gastrointestinal adverse effects.
Indications
Naproxen Sodium is indicated for the relief of mild to moderate pain, such as pain following tooth extraction and other surgeries, primary dysmenorrhea, and headaches. It is also suitable for rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, juvenile arthritis, tendinitis, bursitis, and acute gouty arthritis. It alleviates symptoms like pain, swelling, and limited mobility associated with these conditions.
