Glucosamine Sulfate is a widely used compound in medicine and healthcare, primarily for the treatment of joint diseases, especially osteoarthritis.
Basic Information
English Name: Glucosamine Sulfate
Chemical Formula: C12H28N2O14S
Molecular Weight: 456.42
CAS Registry Number: 14999-43-0
Primary Indications
Glucosamine Sulfate is primarily used to treat joint diseases such as arthritis, rheumatoid arthritis, synovitis, etc. It is a natural component of cartilage matrix and synovial fluid, offering protection and repair to joint cartilage.
Pharmacological Effects
Promotes Cartilage Repair: Glucosamine Sulfate stimulates chondrocytes to produce glycoproteins with normal polymeric structures, aiding in the repair of damaged cartilage.
Inhibits Enzyme Activity: It inhibits the activity of enzymes that can damage joint cartilage, such as collagenase and phospholipase A2, reducing further cartilage damage.
Anti-inflammatory Effects: By inhibiting the production of superoxide free radicals in damaged cells, Glucosamine Sulfate exhibits mild anti-inflammatory effects, helping to alleviate osteoarthritis pain.
Protects Chondrocytes: Prevents the damage of chondrocytes by corticosteroids and certain non-steroidal anti-inflammatory drugs, and reduces the release of endotoxin factors from damaged cells.
